Telmisartan
نویسندگان
چکیده
منابع مشابه
Telmisartan and cardioprotection
Cardiovascular risk reduction has been the target of several large clinical trials in the last decade. As the activation of the renin-angiotensin-aldosterone system (RAAS) plays a central role in the pathogenesis of atherosclerosis and cardiovascular disease, RAAS blockade has been suggested to be among the most efficient cardioprotective interventions, as revealed with the angiotensin converti...
متن کاملTelmisartan/hydrochlorothiazide-induced hepatotoxicity
Corresponding author: Nicola Lucio Liberato MD Internal Medicine Ospedale C. Mira Piazzale Volontari del Sangue 27022 Casorate Primo (PV), Italy Phone: +390290040224 Fax: +390290040304 E-mail: lucio_liberato@ ospedali.pavia.it 1 Internal Medicine, Azienda Ospedaliera della Provincia di Pavia, Ospedale Civile “Asilo Vittoria”, Mortara (PV), Italy 2 Internal Medicine, Azienda Ospedaliera della Pr...
متن کاملA Review on: Telmisartan
Telmisartan is a potent, long-lasting, nonpeptide antagonist of the angiotensin II type-1 (AT1) receptor that is indicated for the treatment of essential hypertension. It selectively inhibits stimulation of the AT1 receptor by angiotensin II without affecting other receptor systems involved in cardiovascular regulation. Very high lipophilicity a unique feature of telmisartan coupled with a high...
متن کاملTelmisartan: the ACE of ARBs?
In 2002, my colleagues and I 1 suggested that blockade of the renin–angiotensin system may prevent diabetes by promoting adipogenesis, thereby allowing redistribution of fat from dangerous visceral and ectopic fat deposits to less-dangerous subcutaneous depots. This hypothesis was based on our observation that angiotensin II inhibits human preadipocyte differentiation.2 We subsequently demonstr...
متن کاملRenoprotection by Telmisartan versus Benazepril in Streptozotocin Induced Diabetic Nephropathy
Diabetic nephropathy (DN) is one of the major causes of end stage renal disease. Angiotensin converting enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB) are preferred for delaying progression of DN. This study compared the preventive renal effects of telmisartan (10 mg/kg, p.o.), an ARB that completely blocks angiotensin action, and benazepril (5 mg/kg, p.o.), an ACE inhibitor, whi...
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ژورنال
عنوان ژورنال: International Journal of Chemical Studies
سال: 2020
ISSN: 2349-8528,2321-4902
DOI: 10.22271/chemi.2020.v8.i4aw.10257